The WDR13 Polyclonal Antibody (PAC061149) is a valuable tool for researchers studying the WD repeat-containing protein 13 (WDR13), a protein involved in various cellular processes. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By targeting the WDR13 protein, this antibody enables precise detection and analysis in different cell types, facilitating in-depth research in fields such as molecular biology and cell biology.
WDR13 is known to play a role in diverse cellular functions, including gene expression regulation, cell cycle control, and protein-protein interactions. Its involvement in these processes suggests its potential importance in various diseases and biological pathways. By utilizing the WDR13 Polyclonal Antibody, researchers can delve deeper into the mechanisms underlying WDR13 function and its implications in health and disease.
Antibody Name:
WDR13 Antibody (PACO61149)
Antibody SKU:
PACO61149
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:200-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human WD repeat-containing protein 13 protein (14-156AA)
IHC image of PACO61149 diluted at 1:300 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
microtubule organizing center, nucleoplasm, plasma membrane
Synonyms:
WD repeat-containing protein 13, WDR13
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. A similar protein in mouse is thought to be a negative regulator of the pancreatic beta cell proliferation. Mice lacking this gene exhibit increased pancreatic islet mass and higher serum insulin levels, and are mildly obese. [provided by RefSeq, Nov 2016]
