The WDR1 Polyclonal Antibody (CAB12163) is a crucial tool for researchers studying the WDR1 protein, which is involved in actin filament disassembly and cellular processes such as cell migration and cytokinesis. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for Western blot applications.WDR1, also known as actin-interacting protein 1, plays a key role in regulating actin dynamics and maintaining cellular structure. Dysregulation of WDR1 has been linked to various diseases, including cancer and neurological disorders.
By targeting WDR1 with this polyclonal antibody, researchers can investigate its function in different cell types and gain insights into its role in cellular processes.The WDR1 Polyclonal Antibody is a valuable tool for studies in cell biology, cancer research, and neurobiology. Its ability to detect and analyze WDR1 protein expression in various cellular contexts makes it an essential reagent for understanding the molecular mechanisms underlying disease processes and identifying potential therapeutic targets.
Product Name:
WDR1 Rabbit Polyclonal Antibody
SKU:
CAB12163
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-500 of human WDR1 (NP_059830.1).
This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
9948
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using WDR1 Rabbit pAb (CAB12163) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
