The WBP11 Polyclonal Antibody (CAB16191) is an essential tool for researchers studying the WBP11 protein, which plays a key role in cellular processes such as RNA splicing and transcription regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.By targeting the WBP11 protein, this antibody enables the detection and analysis of WBP11 expression in various cell types, making it a valuable asset for studies in molecular biology and gene regulation. Understanding the function and regulation of WBP11 is crucial for advancing our knowledge of how cells control gene expression and maintain proper cellular function.
Furthermore, the WBP11 Polyclonal Antibody can be a useful tool in research related to cancer, developmental biology, and neurological disorders, where dysregulation of gene expression can play a significant role in disease progression. By delving into the intricacies of WBP11 activity, researchers can uncover new insights that may lead to the development of novel therapeutic strategies targeting these challenging conditions.
Product Name:
WBP11 Rabbit Polyclonal Antibody
SKU:
CAB16191
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 540-641 of human WBP11 (NP_057396.1).
This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
Purification Method:
Affinity purification
Gene ID:
51729
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using WBP11 Rabbit pAb (CAB16191) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
