The WASL Rabbit Monoclonal Antibody (CAB2270) is a cutting-edge tool for researchers investigating the protein WASL, an important regulator of actin dynamics and cell migration. This monoclonal antibody, developed using rabbit immunization techniques, demonstrates high specificity and sensitivity for detecting WASL in human samples, making it an ideal choice for Western blot and immunohistochemistry studies.WASL, also known as Wiskott-Aldrich syndrome protein-like, is a key player in cellular processes such as cytoskeleton rearrangement and cell motility.
Dysregulation of WASL has been implicated in various diseases, including cancer and immune disorders, highlighting its potential as a therapeutic target. By using the CAB2270 antibody, researchers can gain valuable insights into the function and expression of WASL in different cell types and disease states, paving the way for innovative research in cell biology and drug development.
Product Name:
N-WASP/WASL Rabbit Monoclonal Antibody
SKU:
CAB2270
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human N-WASP/WASL (O00401).
This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension.
Purification Method:
Affinity purification
Gene ID:
8976
Clone Number:
ARC0737
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using N-WASP/N-WASP/WASL Rabbit mAb (CAB2270) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
