UniProt Protein Function: | CCDC53: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. Belongs to the CCDC53 family.Chromosomal Location of Human Ortholog: 12q23.2Cellular Component: intracellular membrane-bound organelle; early endosome; actin cytoskeletonMolecular Function: protein bindingBiological Process: protein transport |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9Y3C0 |
NCBI GenInfo Identifier: | 7705622 |
NCBI Gene ID: | 51019 |
NCBI Accession: | NP_057137.1 |
UniProt Secondary Accession: | Q9Y3C0,Q53FF0, Q6IAI4, Q96QK0, B2RC74 |
UniProt Related Accession: | Q9Y3C0 |
Molecular Weight: | 21,173 Da |
NCBI Full Name: | WASH complex subunit CCDC53 isoform 1 |
NCBI Synonym Full Names: | coiled-coil domain containing 53 |
NCBI Official Symbol: | CCDC53Â Â |
NCBI Official Synonym Symbols: | CGI-116Â Â |
NCBI Protein Information: | WASH complex subunit CCDC53; coiled-coil domain-containing protein 53 |
UniProt Protein Name: | WASH complex subunit CCDC53 |
UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 53 |
Protein Family: | WASH complex |
UniProt Gene Name: | CCDC53Â Â |
UniProt Entry Name: | CCD53_HUMAN |