The WASF3 Polyclonal Antibody (CAB16274) is a valuable tool for researchers studying the WASF3 protein, a key regulator of cell migration and invasion. This antibody is raised in rabbits and has been validated for use in Western blot applications, allowing for the detection and analysis of WASF3 in various cell types.WASF3 plays a critical role in the rearrangement of the actin cytoskeleton, which is essential for cellular processes such as cell motility and invasion. Dysregulation of WASF3 has been implicated in various diseases, including cancer, where increased expression of WASF3 is associated with more aggressive tumor behavior.
By utilizing the WASF3 Polyclonal Antibody, researchers can further investigate the function of WASF3 and its role in disease progression. This antibody provides a reliable tool for studying the molecular mechanisms underlying cell migration and invasion, offering insights that could potentially lead to the development of targeted therapies for cancer and other related diseases.
Product Name:
WASF3 Rabbit Polyclonal Antibody
SKU:
CAB16274
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human WASF3 (NP_001278894.1).
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants
Purification Method:
Affinity purification
Gene ID:
10810
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using WASF3 Rabbit pAb (CAB16274) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
