WASF1 Rabbit Polyclonal Antibody (CAB14624)
- SKU:
- CAB14624
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | WASF1 Rabbit Polyclonal Antibody |
SKU: | CAB14624 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human WASF1 (NP_001020107.1). |
Sequence: | VARA APVC ETVP VHPL PQGE VQGL PPPP PPPP LPPP GIRP SSPV TVTA LAHP PSGL HPTP STAP GPHV PLMP PSPP SQVI PASE PKRH PSTL PVIS DARS VLLE AIRK GIQL RKVE EQRE QEAK HERI ENDV ATIL SRRI AVEY SDSE DDSE FDEV DWLE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | WAVE; SCAR1; WAVE1; NEDALVS; WASF1 |
Positive Sample: | U-87MG,DU145,HeLa,K-562,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cytoplasm, cytoskeleton, focal adhesion, synapse. |
Calculated MW: | 62kDa |
Observed MW: | 62kDa |
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8936 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |