The WARS2 Polyclonal Antibody (CAB15384) is specifically designed for research involving WARS2, a mitochondrial protein responsible for catalyzing the aminoacylation of tRNATrp in the cytoplasm. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.WARS2 is involved in protein translation and is essential for maintaining mitochondrial function and cellular energy production. Dysregulation of WARS2 has been implicated in various diseases, including metabolic disorders and neurodegenerative conditions.
By targeting WARS2 with this antibody, researchers can better understand its role in these pathological processes and potentially develop targeted therapies.The WARS2 Polyclonal Antibody enables detection and analysis of WARS2 protein expression in different cell types and tissues, making it an essential tool for studies in mitochondrial biology, biochemistry, and disease mechanisms. Its versatility and specificity make it a valuable asset for scientists investigating the intricacies of WARS2 functions and dysfunctions in various biological contexts.
Product Name:
WARS2 Rabbit Polyclonal Antibody
SKU:
CAB15384
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 211-360 of human WARS2 (NP_056651.1).
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. This gene encodes the mitochondrial tryptophanyl-tRNA synthetase. Two alternative transcripts encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
10352
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using WARS2 Rabbit pAb (CAB15384) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
