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Tryptophanyl-tRNA synthetase Rabbit Polyclonal Antibody (CAB5758)

SKU:
CAB5758
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cardiovascular
  • Cardiovascular Antibodies Anti-WARS Antibody CAB5758
  • Cardiovascular Antibodies Anti-WARS Antibody CAB5758
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Tryptophanyl-tRNA synthetase Rabbit Polyclonal Antibody
SKU:CAB5758
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human Tryptophanyl-tRNA synthetase 1 (NP_776049.1).
Sequence:MPNS EPAS LLEL FNSI ATQG ELVR SLKA GNAS KDEI DSAV KMLV SLKM SYKA AAGE DYKA DCPP GNPA PTSN HGPD ATEA EEDF VDPW TVQT SSAK GIDY DKLI VRFG SSKI DKEL INRI ERAT GQRP HHFL RRGI FFSH RDMN QVLD AYEN KKPF YLYT GRGP SSEA MHVG HLIP FIFT KWLQ DVFN VPLV IQMT DDEK YLWK DLTL DQAY SYAV ENAK DIIA CGFD INKT FIFS DLDY MGMS SGFY KNVV KIQK HVTF NQVK GIFG FT
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:HMN9; WARS; IFI53; IFP53; GAMMA-2; Tryptophanyl-tRNA synthetase 1
Positive Sample:MCF7,SW480,293T,HeLa,mouse brain,mouse lung,rat brain,HL-60,HepG2
Conjugate:Unconjugated
Cellular Localization:Cytoplasm.
Calculated MW:53kDa
Observed MW:53-55kDa

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:7453
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using Tryptophanyl-tRNA synthetase 1 antibody (CAB5758) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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