The WAC Polyclonal Antibody (CAB17703) is a highly specific antibody designed for research involving the WAC protein, a key regulator of lysosomal function and autophagy. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications. It binds specifically to the WAC protein, allowing for accurate detection and analysis in various cell types.The WAC protein is involved in the maintenance of cellular homeostasis by regulating lysosomal function and autophagy, processes critical for cellular health and survival.
Dysregulation of WAC has been linked to various diseases, including neurodegenerative disorders and cancer. Understanding the function of WAC can provide valuable insights into these conditions and potentially lead to the development of new therapeutic strategies.Overall, the WAC Polyclonal Antibody is a valuable tool for researchers studying lysosomal function, autophagy, and the role of WAC in disease pathogenesis. Its high specificity and reactivity make it an ideal choice for studies in cell biology, molecular biology, and cancer research.
Product Name:
WAC Rabbit Polyclonal Antibody
SKU:
CAB17703
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human WAC (NP_057712.2).
The protein encoded by this gene contains a WW domain, which is a protein module found in a wide range of signaling proteins. This domain mediates protein-protein interactions and binds proteins containing short linear peptide motifs that are proline-rich or contain at least one proline. This gene product shares 94% sequence identity with the WAC protein in mouse, however, its exact function is not known. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
51322
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using WAC Rabbit pAb (CAB17703) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
