The VTCN1 Polyclonal Antibody (CAB10412) is a valuable tool for researchers studying VTCN1, a cell surface protein with immunomodulatory properties. Raised in rabbits, this antibody is highly specific for human samples and has been validated for use in Western blot applications. By binding to the VTCN1 protein, this antibody allows for the detection and analysis of VTCN1 in various cell types, making it an ideal choice for studies in immunology and cancer research.VTCN1, also known as B7-H4, is a crucial regulator of immune responses, playing a role in maintaining immune homeostasis and preventing excessive inflammation.
Its involvement in immune modulation makes it a promising target for research on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of VTCN1 is essential for the development of therapies that can effectively modulate the immune system in these disease contexts.
Product Name:
B7-H4/VTCN1 Rabbit Polyclonal Antibody
SKU:
CAB10412
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human B7-H4/VTCN1 (NP_078902.2).
Cell membrane, Single-pass type I membrane protein.
Calculated MW:
31kDa
Observed MW:
36kDa
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
79679
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using B7-H4/VTCN1 Rabbit pAb (CAB10412) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
