| UniProt Protein Function: | VSIG4: Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Receptor, misc.Chromosomal Location of Human Ortholog: Xq12-q13.3 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| UniProt Code: | Q9Y279 |
| NCBI GenInfo Identifier: | 59799152 |
| NCBI Gene ID: | 11326 |
| NCBI Accession: | Q9Y279.1 |
| UniProt Secondary Accession: | Q9Y279,Q6UXI4 |
| UniProt Related Accession: | Q9Y279 |
| Molecular Weight: | 33,857 Da |
| NCBI Full Name: | V-set and immunoglobulin domain-containing protein 4 |
| NCBI Synonym Full Names: | V-set and immunoglobulin domain containing 4 |
| NCBI Official Symbol: | VSIG4Â Â |
| NCBI Official Synonym Symbols: | CRIg; Z39IGÂ Â |
| NCBI Protein Information: | V-set and immunoglobulin domain-containing protein 4 |
| UniProt Protein Name: | V-set and immunoglobulin domain-containing protein 4 |
| UniProt Synonym Protein Names: | Protein Z39Ig |
| Protein Family: | V-set and immunoglobulin domain-containing protein |
| UniProt Gene Name: | VSIG4Â Â |
| UniProt Entry Name: | VSIG4_HUMAN |
