VPS4B Rabbit Polyclonal Antibody (CAB15758)
- SKU:
- CAB15758
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
Product Name: | VPS4B Rabbit Polyclonal Antibody |
SKU: | CAB15758 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human VPS4B (NP_004860.2). |
Sequence: | MSST SPNL QKAI DLAS KAAQ EDKA GNYE EALQ LYQH AVQY FLHV VKYE AQGD KAKQ SIRA KCTE YLDR AEKL KEYL KNKE KKAQ KPVK EGQP SPAD EKGN DSDG EGES DDPE KKKL QNQL QGAI VIER PN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MIG1; SKD1; SKD1B; VPS4-2; VPS4B |
Positive Sample: | Mouse kidney,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Late endosome membrane, Peripheral membrane protein, Prevacuolar compartment membrane. |
Calculated MW: | 49kDa |
Observed MW: | 48kDa |
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16.
Purification Method: | Affinity purification |
Gene ID: | 9525 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |