The VPS39 Polyclonal Antibody (CAB13082) is a valuable tool for researchers studying the VPS39 protein, which is a key component of the HOPS complex involved in membrane trafficking and fusion processes within cells. This antibody, generated in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications.The VPS39 Polyclonal Antibody specifically targets the VPS39 protein, allowing for accurate detection and analysis in a variety of cell types. This makes it an essential tool for investigations in cell biology, molecular biology, and disease research.
VPS39 plays a crucial role in cellular processes such as endosome maturation, autophagy, and lysosomal biogenesis, making it a promising target for studies related to neurodegenerative disorders, metabolic diseases, and cancer. Understanding the function and regulation of VPS39 can provide insights into the underlying mechanisms of these conditions and potentially lead to the development of novel therapeutic strategies.
Product Name:
VPS39 Rabbit Polyclonal Antibody
SKU:
CAB13082
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 606-875 of human VPS39 (NP_056104.2).
Cytoplasm, Late endosome, Late endosome membrane, Lysosome, Lysosome membrane, Peripheral membrane protein.
Calculated MW:
102kDa
Observed MW:
102kDa
This gene encodes a protein that may promote clustering and fusion of late endosomes and lysosomes. The protein may also act as an adaptor protein that modulates the transforming growth factor-beta response by coupling the transforming growth factor-beta receptor complex to the Smad pathway. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23339
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat brain, using VPS39 Rabbit pAb (CAB13082) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
