The VPS37B Polyclonal Antibody (CAB17770) is a vital tool for researchers studying VPS37B, a key component of the endosomal sorting complex required for transport (ESCRT)-I complex involved in protein trafficking and sorting. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot applications. By targeting the VPS37B protein, this antibody allows for precise detection and analysis in various cell types, facilitating investigations in cell biology, membrane trafficking, and intracellular protein transport.
VPS37B plays a crucial role in endosomal sorting and protein degradation pathways, making it a promising target for understanding cellular processes and disease mechanisms. Dysregulation of VPS37B has been linked to various diseases, including neurodegenerative disorders and viral infections. Investigating the function and regulation of VPS37B using this antibody can provide valuable insights into these disease pathways and potential therapeutic interventions.
Product Name:
VPS37B Rabbit Polyclonal Antibody
SKU:
CAB17770
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-170 of human VPS37B (NP_078943.1).
Enables calcium-dependent protein binding activity. Involved in positive regulation of viral budding via host ESCRT complex. Located in endosome membrane; midbody; and plasma membrane. Part of ESCRT I complex.
Purification Method:
Affinity purification
Gene ID:
79720
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat thymus, using VPS37B Rabbit pAb (CAB17770) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
