VPS37A Rabbit Polyclonal Antibody (CAB14159)
- SKU:
- CAB14159
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | VPS37A Rabbit Polyclonal Antibody |
SKU: | CAB14159 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 224-397 of human VPS37A (NP_689628.2). |
Sequence: | MPDV PDAF PELS ELSV SQLT DMNE QEEV LLEQ FLTL PQLK QIIT DKDD LVKS IEEL ARKN LLLE PSLE AKRQ TVLD KYEL LTQM KSTF EKKM QRQH ELSE SCSA SALQ ARLK VAAH EAEE ESDN IAED FLEG KMEI DDFL SSFM EKRT ICHC RRAK EEKL QQAI AMHS QFHA PL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | HCRP1; PQBP2; SPG53; VPS37A |
Positive Sample: | MCF7,HepG2,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Late endosome membrane, Nucleus, Peripheral membrane protein. |
Calculated MW: | 44kDa |
Observed MW: | 44kDa |
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 137492 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |