The VPS36 Polyclonal Antibody (CAB15157) is a valuable tool for researchers studying VPS36, a key protein involved in the endosomal sorting complex required for transport (ESCRT). This antibody is specifically designed to detect VPS36 in human samples and is validated for use in Western blot applications.VPS36 plays a critical role in the sorting and trafficking of proteins within cells, particularly in the process of multivesicular body (MVB) formation and endosomal sorting. Dysregulation of VPS36 has been implicated in various diseases, including neurodegenerative disorders and viral infections.
By targeting VPS36, researchers can gain insight into the molecular mechanisms underlying these conditions and potentially develop new therapeutic strategies.The VPS36 Polyclonal Antibody (CAB15157) allows for the detection and analysis of VPS36 in a variety of cell types, making it an essential tool for studies in cell biology, molecular biology, and the development of targeted therapeutics. Its high reactivity and specificity make it a reliable choice for researchers looking to further their understanding of ESCRT biology and its implications for human health.
Product Name:
VPS36 Rabbit Polyclonal Antibody
SKU:
CAB15157
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-220 of human VPS36 (NP_057159.2).
Cytoplasm, Endosome, Late endosome, Membrane, Nucleus.
Calculated MW:
44kDa
Observed MW:
43kDa
This gene encodes a protein that is a subunit of the endosomal sorting complex required for transport II (ESCRT-II). This protein complex functions in sorting of ubiquitinated membrane proteins during endocytosis. A similar protein complex in rat is associated with RNA polymerase elongation factor II.
Purification Method:
Affinity purification
Gene ID:
51028
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using VPS36 Rabbit pAb (CAB15157) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
