VPS35 Rabbit Polyclonal Antibody (CAB7117)
- SKU:
- CAB7117
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | VPS35 Rabbit Polyclonal Antibody |
SKU: | CAB7117 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human VPS35 (NP_060676.2). |
Sequence: | MPTT QQSP QDEQ EKLL DEAI QAVK VQSF QMKR CLDK NKLM DALK HASN MLGE LRTS MLSP KSYY ELYM AISD ELHY LEVY LTDE FAKG RKVA DLYE LVQY AGNI IPRL YLLI TVGV VYVK SFPQ SRKD ILKD LVEM CRGV QHPL RGLF LRNY LLQC TRNI LPDE GEPT DEET TGDI SDSM DFVL LNFA EMNK LWVR MQHQ GHSR DREK RERE RQEL RILV GTNL VRLS QLEG VNVE RYKQ IVLT GILE QV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MEM3; PARK17; VPS35 |
Positive Sample: | 293T,K-562,Mouse liver,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Early endosome, Endosome, Late endosome, Membrane, Peripheral membrane protein. |
Calculated MW: | 92kDa |
Observed MW: | 92kDa |
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.
Purification Method: | Affinity purification |
Gene ID: | 55737 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |