VPS26A Rabbit Polyclonal Antibody (CAB14265)
- SKU:
- CAB14265
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | VPS26A Rabbit Polyclonal Antibody |
SKU: | CAB14265 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 256-327 of human VPS26A (NP_004887.2). |
Sequence: | DPTP TMRD VNKK FSVR YFLN LVLV DEED RRYF KQQE IILW RKAP EKLR KQRT NFHQ RFES PESQ ASAE QPEM |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:50 - 1:200 |
Synonyms: | HB58; PEP8A; VPS26; Hbeta58; VPS26A |
Positive Sample: | U-937,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Early endosome, Endosome membrane, Peripheral membrane protein. |
Calculated MW: | 38kDa |
Observed MW: | 40kDa |
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 9559 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |