The VPS13A Polyclonal Antibody (CAB17419) is a valuable tool for researchers studying VPS13A, a protein involved in membrane trafficking and regulation of organelle size. This antibody, developed in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the VPS13A protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential component for research in cell biology and neurodegenerative diseases.VPS13A, also known as vacuolar protein sorting associated protein 13A, plays a crucial role in processes such as lipid transport and autophagy, making it a key player in cellular homeostasis and organelle dynamics.
Its involvement in neurological disorders like Parkinson's disease and Chorea-acanthocytosis underscores its importance in understanding the mechanisms of neurodegeneration. By studying VPS13A, researchers can gain valuable insights into the pathogenesis of these disorders and potentially uncover new therapeutic targets for treatment.
Product Name:
VPS13A Rabbit Polyclonal Antibody
SKU:
CAB17419
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-600 of human VPS13A (NP_150648.2).
The protein encoded by this gene may control steps in the cycling of proteins through the trans-Golgi network to endosomes, lysosomes and the plasma membrane. Mutations in this gene cause the autosomal recessive disorder, chorea-acanthocytosis. Alternative splicing of this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23230
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-87MG cells, using VPS13A Rabbit pAb (CAB17419) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
