The VP40 Monoclonal Antibody (PAC06211) is a valuable tool for researchers studying the Ebola virus and its proteins. This antibody, produced using hybridoma technology, specifically targets the VP40 protein, which plays a crucial role in the assembly and release of Ebola virus particles. Validated for use in various applications including Western blot and immunofluorescence, this monoclonal antibody is highly specific for VP40 and shows minimal cross-reactivity with other proteins.
Its high affinity binding to VP40 allows for accurate and reliable detection and analysis in Ebola virus research.Research on the VP40 protein is essential for understanding the mechanisms of Ebola virus replication and pathogenesis, which is critical for the development of effective treatments and vaccines. The VP40 Monoclonal Antibody is a valuable tool for researchers working towards advancements in the field of virology and infectious diseases.
Antibody Name:
VP40 Antibody (PACO62211)
Antibody SKU:
PACO62211
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Zaire ebolavirus
Immunogen:
Recombinant Zaire ebolavirus Matrix protein VP40 protein (1-326AA)
Western Blot. Positive WB detected in Recombinant protein. All lanes: VP40 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 51 kDa. Observed band size: 51 kDa.
Background:
Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. May facilitate virus budding by interacting with the nucleocapsid and the plasma membrane. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. The hexamer form seems to be involved in budding. The octamer form binds RNA, and may play a role in genome replication (By similarity).
Synonyms:
Matrix protein VP40 (Membrane-associated protein VP40), VP40
UniProt Protein Function:
Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. May facilitate virus budding by interacting with the nucleocapsid and the plasma membrane. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. The hexamer form seems to be involved in budding. The octamer form binds RNA, and may play a role in genome replication ().
