VNN1 Rabbit Polyclonal Antibody (CAB3347)
- SKU:
- CAB3347
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Description
Product Name: | VNN1 Rabbit Polyclonal Antibody |
SKU: | CAB3347 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-415 of human VNN1 (NP_004657.2). |
Sequence: | LLSQ LDSH PSHS AVVN WTSY ASSI EALS SGNK EFKG TVFF DEFT FVKL TGVA GNYT VCQK DLCC HLSY KMSE NIPN EVYA LGAF DGLH TVEG RYYL QICT LLKC KTTN LNTC GDSA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HDLCQ8; Tiff66; VNN1 |
Positive Sample: | 293T,A-431,HepG2,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, GPI-anchor, Lipid-anchor. |
Calculated MW: | 57kDa |
Observed MW: | 60kDa |
This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
Purification Method: | Affinity purification |
Gene ID: | 8876 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |