The VMP1 Polyclonal Antibody (CAB15523) is a valuable tool for researchers studying the VMP1 protein, which is involved in autophagy and endoplasmic reticulum stress responses. This antibody, produced in rabbits, is highly specific to human VMP1 and is validated for use in Western blotting applications. By binding to the VMP1 protein, this antibody allows for accurate detection and analysis in various cell types, making it ideal for studies in cell biology and disease research.VMP1 is a critical player in the regulation of autophagy, a cellular process essential for maintaining cellular homeostasis and responding to stress conditions. Dysregulation of autophagy has been linked to a variety of diseases, including neurodegenerative disorders, cancer, and inflammatory conditions.
Research into the function of VMP1 can provide insights into the mechanisms underlying these diseases and may lead to the development of novel therapeutic strategies targeting autophagy pathways.By utilizing the VMP1 Polyclonal Antibody (CAB15523), researchers can further investigate the role of VMP1 in autophagy and stress responses, ultimately advancing our understanding of cellular processes and disease pathogenesis. This antibody is a valuable tool for any research laboratory interested in exploring the intricate mechanisms of autophagy and its implications for human health.
Product Name:
VMP1 Rabbit Polyclonal Antibody
SKU:
CAB15523
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human VMP1 (NP_112200.2).
This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy.
Purification Method:
Affinity purification
Gene ID:
81671
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse kidney, using VMP1 Rabbit pAb (CAB15523) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
