VMP1 Rabbit Polyclonal Antibody (CAB15523)
- SKU:
- CAB15523
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | VMP1 Rabbit Polyclonal Antibody |
SKU: | CAB15523 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human VMP1 (NP_112200.2). |
Sequence: | KMHI QKIF VIIT FSKH IVEQ MVAF IGAV PGIG PSLQ KPFQ EYLE AQRQ KLHH KSEM GTPQ GENW LSWM FEKL VVVM VCYF ILSI INSM AQSY AKRI QQRL NSEE KTK |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | EPG3; TANGO5; TMEM49; VMP1 |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endoplasmic reticulum, Endoplasmic reticulum-Golgi intermediate compartment membrane, Multi-pass membrane protein, Vacuole membrane. |
Calculated MW: | 46kDa |
Observed MW: | 42kDa |
This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy.
Purification Method: | Affinity purification |
Gene ID: | 81671 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |