VIPR2 Antibody (PACO63731)
- SKU:
- PACO63731
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
VIPR2 Antibody (PACO63731)
The VIPR2 Polyclonal Antibody (PAC063731) is a valuable tool for researchers investigating VIPR2, a G protein-coupled receptor involved in the regulation of various physiological functions, including the control of vasodilation, smooth muscle relaxation, and neurotransmitter release. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications, allowing for the detection and analysis of VIPR2 protein expression in different cell types. Its specificity and sensitivity make it an ideal choice for studies in neuroscience, cardiovascular research, and endocrinology.
VIPR2, also known as Vasoactive intestinal peptide receptor 2, plays a crucial role in modulating the activity of VIP, a neuropeptide with diverse biological functions. Dysregulation of the VIP-VIPR2 signaling pathway has been implicated in various diseases, including neurological disorders, gastrointestinal diseases, and cardiovascular conditions. Investigating the function of VIPR2 is essential for understanding its role in health and disease, and may lead to the development of novel therapeutic approaches targeting this receptor.
| Antibody Name: | VIPR2 Antibody (PACO63731) |
| Antibody SKU: | PACO63731 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Vasoactive intestinal polypeptide receptor 2 protein (24-126AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: MCF-7 whole cell lysate. All lanes: VIPR2 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 50, 47 kDa. Observed band size: 50 kDa. |
| Background: | This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C. |
| Synonyms: | Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Helodermin-preferring VIP receptor) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (PACAP-R3) (VPAC2), VIPR2, VIP2R |
| UniProt Protein Function: | VIPR2: This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C. Belongs to the G-protein coupled receptor 2 family. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 2 Chromosomal Location of Human Ortholog: 7q36.3 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity Biological Process: cell-cell signaling; signal transduction |
| NCBI Summary: | This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011] |
| UniProt Code: | P41587 |
| NCBI GenInfo Identifier: | 2506490 |
| NCBI Gene ID: | 7434 |
| NCBI Accession: | P41587.2 |
| UniProt Secondary Accession: | P41587,Q13053, Q15870, Q53Y09, Q6ZN22, Q9UCW0, |
| UniProt Related Accession: | P41587 |
| Molecular Weight: | 46,756 Da |
| NCBI Full Name: | Vasoactive intestinal polypeptide receptor 2 |
| NCBI Synonym Full Names: | vasoactive intestinal peptide receptor 2 |
| NCBI Official Symbol: | VIPR2Â Â |
| NCBI Official Synonym Symbols: | VPAC2; VPAC2R; VIP-R-2; VPCAP2R; PACAP-R3; DUP7q36.3; PACAP-R-3; C16DUPq36.3Â Â |
| NCBI Protein Information: | vasoactive intestinal polypeptide receptor 2 |
| UniProt Protein Name: | Vasoactive intestinal polypeptide receptor 2 |
| UniProt Synonym Protein Names: | Helodermin-preferring VIP receptor; Pituitary adenylate cyclase-activating polypeptide type III receptor; PACAP type III receptor; PACAP-R-3; PACAP-R3; VPAC2 |
| Protein Family: | Vasoactive intestinal polypeptide receptor |
| UniProt Gene Name: | VIPR2Â Â |
| UniProt Entry Name: | VIPR2_HUMAN |
| Antibodies | ELISA Kits |
| VIPR2 Antibody (PACO05304) | Human VIPR2 / Vasoactive intestinal polypeptide receptor 2 ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
VIPR2 Antibody (PACO20856)
VIPR2 Antibody (PACO05304)
Human VIPR2 / Vasoactive intestinal polypeptide receptor 2 ELISA Kit
