Vinculin Rabbit Monoclonal Antibody (CAB2752)
- SKU:
- CAB2752
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Vinculin Rabbit Monoclonal Antibody |
SKU: | CAB2752 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 800-900 of human Vinculin (NP_054706.1). |
Sequence: | DAKA VAGN ISDP GLQK SFLD SGYR ILGA VAKV REAF QPQE PDFP PPPP DLEQ LRLT DELA PPKP PLPE GEVP PPRP PPPE EKDE EFPE QKAG EVIN QPMM M |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:10000 - 1:300000 IF/ICC,1:50 - 1:200 |
Synonyms: | MV; MVCL; CMD1W; CMH15; HEL114; Vinculin |
Positive Sample: | HeLa,HepG2,RD,Mouse liver,Mouse brain,Rat liver,Rat skeletal muscle,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, adherens junction, cytoskeleton, focal adhesion. |
Calculated MW: | 124kDa |
Observed MW: | 124kDa |
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 7414 |
Clone Number: | ARC51900 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |