Vinculin Rabbit Polyclonal Antibody (CAB1758)
- SKU:
- CAB1758
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Vinculin Rabbit Polyclonal Antibody |
SKU: | CAB1758 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 767-1066 of human Vinculin (NP_003364.1). |
Sequence: | AKRE VENS EDPK FREA VKAA SDEL SKTI SPMV MDAK AVAG NISD PGLQ KSFL DSGY RILG AVAK VREA FQPQ EPDF PPPP PDLE QLRL TDEL APPK PPLP EGEV PPPR PPPP EEKD EEFP EQKA GEVI NQPM MMAA RQLH DEAR KWSS KGND IIAA AKRM ALLM AEMS RLVR GGSG TKRA LIQC AKDI AKAS DEVT RLAK EVAK QCTD KRIR TNLL QVCE RIPT ISTQ LKIL STVK ATML GRTN ISDE ESEQ ATEM LVHN AQNL MQSV KETV REAE AASI KIRT DAGF TLRW VRKT PWYQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MV; MVCL; CMD1W; CMH15; HEL114; Vinculin |
Positive Sample: | HeLa,PC-12,RD,Mouse lung,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, adherens junction, cytoskeleton, focal adhesion. |
Calculated MW: | 124kDa |
Observed MW: | 124kDa |
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 7414 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |