The VGLL4 Polyclonal Antibody (CAB18248) is a valuable tool for researchers studying VGLL4, a transcription cofactor that plays a key role in various cellular processes, including cell growth, differentiation, and development. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for Western blot applications. By targeting the VGLL4 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it a versatile tool for studies in molecular biology and cancer research.
VGLL4, also known as Vestigial-like family member 4, is essential for regulating gene expression and controlling cell fate decisions. Its involvement in signaling pathways related to cell proliferation and survival makes it a promising target for investigating mechanisms underlying disease progression, including cancer and developmental disorders. Research on VGLL4 may provide valuable insights into potential therapeutic strategies for targeting aberrant cellular pathways in these conditions.
Product Name:
Vgll4 Rabbit Polyclonal Antibody
SKU:
CAB18248
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of mouse Vgll4 (NP_808351.1).
Predicted to enable transcription coactivator binding activity. Involved in several processes, including negative regulation of cardiac muscle cell proliferation; negative regulation of hippo signaling; and positive regulation of cellular protein catabolic process. Located in nucleus. Is expressed in lung; submandibular gland primordium; tooth; and vibrissa. Orthologous to human VGLL4 (vestigial like family member 4).
Purification Method:
Affinity purification
Gene ID:
232334
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from OVCAR3 cells, using Vgll4 Rabbit pAb (CAB18248) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.