The VEPH1 Polyclonal Antibody (CAB8510) is a valuable tool for researchers studying the VEPH1 protein, a key regulator of cell migration and invasion. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to VEPH1, the antibody enables accurate detection and analysis of this protein in a variety of cell types, making it essential for research in cell biology and cancer metastasis.VEPH1, also known as vascular endothelial-phosphoprotein homologue 1, plays a crucial role in controlling cell motility and invasion, processes that are often dysregulated in cancer progression.
Understanding the function of VEPH1 is vital for uncovering potential therapeutic targets in cancer treatment and developing strategies to inhibit metastasis. By studying the mechanisms by which VEPH1 regulates cell movement, researchers can gain valuable insights into the biology of cancer and potentially identify new avenues for intervention.
Product Name:
VEPH1 Rabbit Polyclonal Antibody
SKU:
CAB8510
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 448-547 of human VEPH1 (NP_078897.2).
Predicted to enable phosphatidylinositol-5-phosphate binding activity. Involved in negative regulation of SMAD protein signal transduction and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be active in plasma membrane.
Purification Method:
Affinity purification
Gene ID:
79674
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using VEPH1 antibody (CAB8510) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
