The VEPH1 Polyclonal Antibody (CAB15228) is a valuable tool for researchers studying the VEPH1 protein, which is involved in cellular signaling and regulation processes. This antibody, generated in rabbits, is highly specific for human samples and is optimized for Western blot applications. By binding to the VEPH1 protein, this antibody allows for the detection and analysis of VEPH1 in various cell types, making it ideal for studies in cell biology and signaling pathways.VEPH1, a regulator of actin dynamics and cytoskeletal organization, is essential for cellular functions such as cell migration, adhesion, and polarity.
Dysregulation of VEPH1 has been implicated in diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases, highlighting the importance of studying its role in cellular processes. Understanding the function of VEPH1 can provide insights into potential therapeutic targets for these diseases and lead to the development of novel treatment strategies.
Product Name:
VEPH1 Rabbit Polyclonal Antibody
SKU:
CAB15228
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 448-547 of human VEPH1 (NP_078897.2).
Predicted to enable phosphatidylinositol-5-phosphate binding activity. Involved in negative regulation of SMAD protein signal transduction and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be active in plasma membrane.
Purification Method:
Affinity purification
Gene ID:
79674
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using VEPH1 Antibody (CAB15228) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5s.
