The VentX Polyclonal Antibody (CAB7467) is a valuable tool for researchers studying VentX, a transcription factor known for its role in cellular development and differentiation. This antibody, generated in rabbits, exhibits high reactivity with VentX in human samples and is validated for use in various applications, including Western blotting.VentX is a critical regulator of gene expression involved in various cellular processes, including cell fate determination and tissue development. Its dysregulation has been implicated in diseases such as cancer and developmental disorders, making it a promising target for therapeutic interventions. By using the VentX Polyclonal Antibody, researchers can explore the functions and mechanisms of VentX in different cell types, advancing our understanding of its involvement in various biological processes.
With its specificity and sensitivity, the VentX Polyclonal Antibody is an essential tool for researchers in the fields of developmental biology, stem cell research, and regenerative medicine. By enabling the detection and analysis of VentX protein, this antibody facilitates investigations into the molecular mechanisms underlying cellular differentiation and tissue regeneration, ultimately paving the way for novel therapeutic strategies in regenerative medicine.
Product Name:
VENTX Rabbit Polyclonal Antibody
SKU:
CAB7467
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-258 of human VENTX (NP_055283.1).
Jurkat,A-549,HepG2,SH-SY5Y,Mouse spinal cord,Rat bone marrow
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
28kDa
Observed MW:
28kDa
This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromosome X may lead to antigen production in certain melanomas.
Purification Method:
Affinity purification
Gene ID:
27287
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using VENTX antibody (CAB7467) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
