The VEGFR2/KDR/FLK-1/CD309 Polyclonal Antibody is a crucial tool for researchers studying vascular endothelial growth factor receptor 2 (VEGFR2), also known as kinase insert domain receptor (KDR) or fetal liver kinase-1 (FLK-1). This antibody, produced in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blot, immunohistochemistry, and flow cytometry.VEGFR2 is a key player in angiogenesis, the process by which new blood vessels form from pre-existing vessels. It is essential for normal development and function of blood vessels, making it a significant target for research in cancer, cardiovascular diseases, and other conditions characterized by abnormal blood vessel formation.
By using the VEGFR2/KDR/FLK-1/CD309 Polyclonal Antibody, researchers can detect and analyze the expression of VEGFR2 in different cell types and tissues, providing valuable insights into its role in angiogenesis and potential as a therapeutic target. This antibody is an essential tool for advancing our understanding of VEGFR2 biology and developing novel treatments for diseases involving aberrant blood vessel growth.
Product Name:
VEGFR2/KDR/Flk-1/CD309 Polyclonal Antibody
SKU:
CAB24671
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-762 of mouse VEGFR2/KDR/Flk-1/CD309(NP_034742.2).
Enables growth factor binding activity and vascular endothelial growth factor-activated receptor activity. Involved in several processes, including circulatory system development; peptidyl-tyrosine autophosphorylation; and positive regulation of vasculogenesis. Acts upstream of or within several processes, including animal organ development; positive regulation of cell population proliferation; and vasculature development. Located in several cellular components, including cell junction; endosome; and external side of plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in several diseases, including adhesions of uterus; artery disease (multiple); gastrointestinal system cancer (multiple); macular degeneration (multiple); and pancreatic cancer (multiple). Orthologous to human KDR (kinase insert domain receptor).
Purification Method:
Affinity purification
Gene ID:
16542
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse lung, using VEGFR2/KDR/Flk-1/CD309 Rabbit pAb (CAB24671) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
