The VEGFB Polyclonal Antibody (CAB2132) is a valuable tool for researchers studying vascular endothelial growth factor B (VEGFB), a protein involved in angiogenesis and vascular development. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting VEGFB in various samples, particularly in Western blot applications. VEGFB is known for its role in promoting blood vessel growth and maintenance, making it a key player in processes like wound healing and tissue regeneration. Dysregulation of VEGFB has been linked to diseases such as cancer, diabetic retinopathy, and cardiovascular disorders, highlighting its importance as a therapeutic target.
By using the VEGFB Polyclonal Antibody, researchers can accurately detect and analyze VEGFB levels in different cell types and tissues, furthering our understanding of its biological functions and potential applications in disease treatment. This antibody is essential for studies investigating VEGFB signaling pathways, angiogenesis regulation, and therapeutic interventions targeting VEGFB activity.
Product Name:
VEGFB Rabbit Polyclonal Antibody
SKU:
CAB2132
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-121 of human VEGFB (NP_003368.1).
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
7423
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat heart, using VEGFB Rabbit pAb (CAB2132) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
