VEGFR1 Rabbit Monoclonal Antibody (CAB19132)
- SKU:
- CAB19132
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Description
Product Name: | VEGFR1 Rabbit Monoclonal Antibody |
SKU: | CAB19132 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human VEGFR1 (P17948). |
Sequence: | MVSY WDTG VLLC ALLS CLLL TGSS SGSK LKDP ELSL KGTQ HIMQ AGQT LHLQ CRGE AAHK WSLP EMVS KESE RLSI TKSA CGRN GKQF CSTL TLNT AQAN |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FLT; FLT-1; VEGFR1; VEGFR-1; FRT |
Positive Sample: | Rat heart,Rat brain,Mouse lung,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Endosome, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 151kDa |
Observed MW: | 180kDa |
This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Purification Method: | Affinity purification |
Gene ID: | 2321 |
Clone Number: | ARC0363 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |