The VDAC2 Polyclonal Antibody (CAB18683) is a valuable tool for researchers studying the Voltage-Dependent Anion Channel 2 (VDAC2) protein. VDAC2 is a mitochondrial protein involved in regulating cell metabolism, apoptosis, and cell survival. The antibody, generated in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.By targeting the VDAC2 protein, this antibody allows for the detection and analysis of VDAC2 expression in various cell types, making it ideal for research in mitochondrial biology, cell death pathways, and cancer research.
Understanding the role of VDAC2 is essential for unraveling its functions in cellular processes and diseases, paving the way for potential therapeutic interventions in disorders where VDAC2 dysregulation is implicated.
Product Name:
VDAC2 Rabbit Polyclonal Antibody
SKU:
CAB18683
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human VDAC2 (NP_003366.2).
This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7417
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using VDAC2 Rabbit pAb (CAB18683) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
