The VDAC1 Rabbit Monoclonal Antibody (CAB19707) is a crucial tool for researchers studying the Voltage-Dependent Anion Channel 1 (VDAC1) protein, a key player in cellular energy metabolism and apoptosis. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity for detecting VDAC1 in human samples, making it an ideal choice for various research applications such as immunohistochemistry and flow cytometry.VDAC1 is a mitochondrial protein that plays a vital role in regulating the flux of ions and metabolites across the mitochondrial outer membrane, influencing cellular energy production and survival.
Dysregulation of VDAC1 has been implicated in numerous diseases, including cancer, neurodegenerative disorders, and metabolic diseases. By targeting VDAC1 with this antibody, researchers can gain insights into its function and potential therapeutic implications in these pathological conditions.Overall, the VDAC1 Rabbit Monoclonal Antibody (CAB19707) offers a reliable and specific tool for investigating the biology of VDAC1 and its impact on cellular processes, providing valuable information for advancing our understanding of disease mechanisms and developing targeted therapies.
Product Name:
VDAC1 Rabbit Monoclonal Antibody
SKU:
CAB19707
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human VDAC1 (P21796).
This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
Purification Method:
Affinity purification
Gene ID:
7416
Clone Number:
ARC0187
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using VDAC1 Rabbit mAb (CAB19707) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
