VCP Rabbit Polyclonal Antibody (CAB2795)
- SKU:
- CAB2795
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | VCP Rabbit Polyclonal Antibody |
SKU: | CAB2795 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 460-770 of human VCP (NP_009057.1). |
Sequence: | NPSA LRET VVEV PQVT WEDI GGLE DVKR ELQE LVQY PVEH PDKF LKFG MTPS KGVL FYGP PGCG KTLL AKAI ANEC QANF ISIK GPEL LTMW FGES EANV REIF DKAR QAAP CVLF FDEL DSIA KARG GNIG DGGG AADR VINQ ILTE MDGM STKK NVFI IGAT NRPD IIDP AILR PGRL DQLI YIPL PDEK SRVA ILKA NLRK SPVA KDVD LEFL AKMT NGFS GADL TEIC QRAC KLAI RESI ESEI RRER ERQT NPSA MEVE EDDP VPEI RRDH FEEA MRFA RRSV SDND IRKY EMFA QTLQ QSRG FGS |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | p97; TERA; CDC48; FTDALS6; VCP |
Positive Sample: | HeLa,K-562,SH-SY5Y,Mouse brain,Mouse spleen,Mouse kidney,Rat liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endoplasmic reticulum, Nucleus, cytosol. |
Calculated MW: | 89kDa |
Observed MW: | 90kDa |
This gene encodes a member of the AAA ATPase family of proteins. The encoded protein plays a role in protein degradation, intracellular membrane fusion, DNA repair and replication, regulation of the cell cycle, and activation of the NF-kappa B pathway. This protein forms a homohexameric complex that interacts with a variety of cofactors and extracts ubiquitinated proteins from lipid membranes or protein complexes. Mutations in this gene cause IBMPFD (inclusion body myopathy with paget disease of bone and frontotemporal dementia), ALS (amyotrophic lateral sclerosis) and Charcot-Marie-Tooth disease in human patients.
Purification Method: | Affinity purification |
Gene ID: | 7415 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |