The VCAM1 Rabbit Monoclonal Antibody (CAB19131) is a valuable tool for research involving VCAM1, a cell adhesion molecule involved in inflammation and immune response regulation. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in various applications including Western blot and immunohistochemistry.VCAM1 plays a crucial role in the recruitment of leukocytes to sites of inflammation and is implicated in the pathogenesis of several inflammatory diseases such as atherosclerosis and rheumatoid arthritis.
By targeting VCAM1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.With its high specificity and sensitivity, the VCAM1 Rabbit Monoclonal Antibody is an essential tool for studies in immunology, cardiovascular biology, and inflammatory disease research. Its ability to detect and analyze VCAM1 expression in different cell types makes it a versatile reagent for investigating the role of VCAM1 in various physiological and pathological processes.
Product Name:
VCAM1 Rabbit Monoclonal Antibody
SKU:
CAB19131
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 640-739 of human VCAM1 (P19320).
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
7412
Clone Number:
ARC0312
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using VCAM1 Rabbit mAb (CAB19131) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
