VAV3 Rabbit Polyclonal Antibody (CAB15385)
- SKU:
- CAB15385
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | VAV3 Rabbit Polyclonal Antibody |
SKU: | CAB15385 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 560-680 of human VAV3 (NP_006104.4). |
Sequence: | DNCG RVNS GEQG TLKL PEKR TNGL RRTP KQVD PGLP KMQV IRNY SGTP PPAL HEGP PLQL QAGD TVEL LKGD AHSL FWQG RNLA SGEV GFFP SDAV KPCP CVPK PVDY SCQP WYAG AMER L |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | VAV3 |
Positive Sample: | Jurkat,Mouse brain,Mouse lung,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, immunological synapse, plasma membrane |
Calculated MW: | 98kDa |
Observed MW: | 105kDa |
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10451 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |