The VAV3 Polyclonal Antibody (CAB15385) is a specialized tool designed for researchers studying the VAV3 protein, a key player in various cellular processes such as cell migration, adhesion, and signaling pathways. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications.With its ability to specifically bind to the VAV3 protein, this antibody enables researchers to detect and analyze VAV3 expression in a variety of cell types, allowing for in-depth investigation into its role in signaling cascades and its potential implications in cancer progression and other diseases.
By targeting the VAV3 protein, researchers can gain valuable insights into the molecular mechanisms underlying cellular functions and pathologies, paving the way for the development of targeted therapies and diagnostic tools.
Product Name:
VAV3 Rabbit Polyclonal Antibody
SKU:
CAB15385
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 560-680 of human VAV3 (NP_006104.4).
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
10451
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using VAV3 Rabbit pAb (CAB15385) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 2s.
