The Vav2 Polyclonal Antibody (CAB9483) is a valuable tool for researchers studying the Vav2 protein, a key regulator of cytoskeletal dynamics and cell migration. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Vav2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential tool for studies in cell biology and cancer research.
Vav2 is a guanine nucleotide exchange factor that plays a crucial role in signaling pathways that control cell migration, proliferation, and differentiation. Dysregulation of Vav2 activity has been implicated in various diseases, including cancer and autoimmune disorders, making it an attractive target for therapeutic interventions. By understanding the function of Vav2, researchers can uncover new insights into disease mechanisms and potentially identify novel treatment strategies.
Product Name:
VAV2 Rabbit Polyclonal Antibody
SKU:
CAB9483
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 570-700 of human VAV2 (NP_001127870.1).
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7410
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using VAV2 Rabbit pAb (CAB9483) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
