The Vav2 Polyclonal Antibody (CAB19883) is a valuable tool for researchers studying Vav2, a guanine nucleotide exchange factor involved in cell signaling and cytoskeletal reorganization. This rabbit-derived antibody is highly specific to human samples and has been validated for use in Western blotting applications. By targeting the Vav2 protein, this antibody allows for the detection and analysis of Vav2 expression in various cell types, making it an ideal choice for studies in cell biology and cancer research.Vav2 is known for its role in regulating cell migration, proliferation, and survival, making it a key player in processes such as immune response and cancer progression.
By targeting Vav2 with this antibody, researchers can gain insight into the mechanisms underlying these complex biological processes and potentially identify new therapeutic targets for diseases such as cancer and autoimmune disorders. Overall, the Vav2 Polyclonal Antibody is a valuable tool for unraveling the functions of Vav2 and its implications in various physiological and pathological conditions.
Product Name:
[KO Validated] VAV2 Rabbit Polyclonal Antibody
SKU:
CAB19883
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 570-700 of human VAV2 (NP_001127870.1).
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7410
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and VAV2 knockout (KO) HeLa cells, using [KO Validated] VAV2 Rabbit pAb (CAB19883) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
