The Vat1 Polyclonal Antibody (CAB17077) is a valuable tool for researchers studying the Vat1 protein, which is involved in vesicle transport and cellular trafficking. This antibody, developed using rabbits, is highly specific to human samples and is approved for use in Western blot applications. By binding to Vat1, this antibody enables researchers to detect and analyze the protein in various cell types, making it ideal for studies in cell biology and neuroscience.Vat1 is a key player in the transport of vesicles within cells, playing a crucial role in maintaining cellular function and communication.
By studying Vat1, researchers can gain insights into processes such as neurotransmitter release, protein trafficking, and organelle biogenesis. This antibody is a valuable tool for investigating the function of Vat1 in normal cellular processes and its potential role in neurodegenerative diseases, such as Alzheimer's and Parkinson's. Understanding the role of Vat1 in cellular trafficking is essential for developing targeted therapies for diseases related to vesicle transport dysfunction.
Product Name:
[KO Validated] VAT1 Rabbit Polyclonal Antibody
SKU:
CAB17077
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human VAT1 (NP_006364.2).
Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins.
Purification Method:
Affinity purification
Gene ID:
10493
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] VAT1 Rabbit pAb (CAB17077) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.
