The VASP Rabbit Monoclonal Antibody (CAB8862) is a valuable tool for researchers studying the Vasodilator-Stimulated Phosphoprotein (VASP). This antibody, produced in rabbits, is highly specific and reactive to human samples, making it ideal for a variety of research applications.VASP plays a crucial role in actin dynamics and cell migration, making it an important protein to study in the fields of cell biology and cancer research. The VASP Rabbit Monoclonal Antibody binds specifically to VASP, allowing for accurate detection and analysis in various cell types.
By understanding the function and regulation of VASP, researchers can gain insights into processes such as cell adhesion, migration, and invasion, which are important in cancer progression and metastasis. The VASP Rabbit Monoclonal Antibody is validated for use in Western blot applications, providing researchers with a reliable tool for their studies.Overall, the VASP Rabbit Monoclonal Antibody is a valuable resource for researchers looking to deepen their understanding of VASP and its implications in various cellular processes and diseases.
Product Name:
VASP Rabbit Monoclonal Antibody
SKU:
CAB8862
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human VASP (P50552).
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Purification Method:
Affinity purification
Gene ID:
7408
Clone Number:
ARC1329
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using VASP Rabbit mAb (CAB8862) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
