The VASH1 Polyclonal Antibody (CAB12569) is a cutting-edge tool designed for researchers studying the vasohibin-1 (VASH1) protein. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the VASH1 protein, this antibody allows for the detection and analysis of VASH1 expression in various cell types, making it a valuable asset for studies in vascular biology and cancer research.VASH1 is a key player in angiogenesis regulation and has been shown to have anti-angiogenic effects, making it a promising target for therapeutic interventions in diseases such as cancer.
By understanding the role of VASH1 in regulating blood vessel formation, researchers can potentially develop novel strategies for treating tumor growth and other disorders associated with abnormal blood vessel development. The VASH1 Polyclonal Antibody is a valuable tool for advancing our understanding of VASH1 function and its implications in disease pathology.
Product Name:
VASH1 Rabbit Polyclonal Antibody
SKU:
CAB12569
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human VASH1 (NP_055724.1).
Enables actin binding activity and metallocarboxypeptidase activity. Involved in negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell migration; and proteolysis. Acts upstream of or within several processes, including negative regulation of endothelial cell migration; negative regulation of endothelial cell proliferation; and negative regulation of lymphangiogenesis. Located in apical part of cell; endoplasmic reticulum; and extracellular space. Implicated in liver cirrhosis and portal hypertension. Biomarker of liver cirrhosis.
Purification Method:
Affinity purification
Gene ID:
22846
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using VASH1 antibody (CAB12569) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
