The VAPA Polyclonal Antibody (CAB12939) is a vital tool for researchers studying VAPA, a protein involved in cellular processes such as lipid metabolism, ER-Golgi membrane trafficking, and autophagy. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot assays. By specifically binding to VAPA, researchers can effectively detect and analyze this protein in a variety of cell types, making it well-suited for investigations in cell biology and neurobiology.
VAPA, also known as VAMP-associated protein A, plays a crucial role in maintaining cellular homeostasis and regulating intracellular membrane dynamics. Its involvement in lipid transport and cellular signaling pathways makes it a promising target for research into metabolic disorders, neurodegenerative diseases, and cancer. Understanding the function of VAPA is essential for developing targeted therapies that modulate lipid metabolism and intracellular trafficking processes.
Product Name:
VAPA Rabbit Polyclonal Antibody
SKU:
CAB12939
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 137-227 of human VAPA (NP_919415.2).
Endoplasmic reticulum membrane, Single-pass type IV membrane protein.
Calculated MW:
28kDa
Observed MW:
28kDa
The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Purification Method:
Affinity purification
Gene ID:
9218
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using VAPA Rabbit pAb (CAB12939) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
