The Vang-like Protein 2 Polyclonal Antibody (CAB7825) is a valuable tool for researchers studying Vang-like protein 2, a protein involved in the regulation of planar cell polarity and cell migration. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blotting applications. By targeting the Vang-like protein 2, this antibody allows for the detection and analysis of this important protein in various cell types, making it an essential tool for studies in cell biology and developmental biology.
Vang-like protein 2 plays a crucial role in coordinating cell movements and tissue organization during development, making it a key player in processes such as embryogenesis and organogenesis. Its function in regulating cell polarity and migration also suggests potential implications in diseases like cancer, where cell motility and tissue organization are disrupted. By studying the role of Vang-like protein 2, researchers can gain insights into the mechanisms underlying these diseases and potentially identify novel therapeutic targets for intervention.
Product Name:
VANGL2 Rabbit Polyclonal Antibody
SKU:
CAB7825
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human VANGL2 (NP_065068.1).
The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate.
Purification Method:
Affinity purification
Gene ID:
57216
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using VANGL2 Rabbit pAb (CAB7825) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
