The VAMP8 Polyclonal Antibody (CAB13915) is a valuable tool for researchers studying VAMP8, a critical protein involved in membrane fusion and vesicle trafficking. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the VAMP8 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in cell biology and neuroscience.VAMP8, also known as vesicle-associated membrane protein 8, plays a pivotal role in intracellular membrane fusion events, particularly in the regulation of vesicle trafficking within the cell. Understanding the function and regulation of VAMP8 is essential for unraveling the mechanisms underlying cellular communication, secretion, and synaptic transmission.
Research into VAMP8 may provide valuable insights into neurological disorders, metabolic diseases, and other conditions related to vesicle transport and membrane dynamics.Overall, the VAMP8 Polyclonal Antibody (CAB13915) is a reliable tool for investigating the intricate processes of membrane fusion and vesicle trafficking mediated by VAMP8. Its high specificity and sensitivity make it a valuable asset for researchers seeking to explore the functional roles and molecular mechanisms of VAMP8 in various biological systems.
Product Name:
VAMP8 Rabbit Polyclonal Antibody
SKU:
CAB13915
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human VAMP8 (NP_003752.2).
Cell membrane, Early endosome membrane, Late endosome membrane, Lysosome membrane, Single-pass type IV membrane protein.
Calculated MW:
11kDa
Observed MW:
11kDa
This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). The encoded protein is involved in the fusion of synaptic vesicles with the presynaptic membrane.
Purification Method:
Affinity purification
Gene ID:
8673
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using VAMP8 Rabbit pAb (CAB13915) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
