The VAMP7 Polyclonal Antibody (PACO31036) is a valuable tool for research involving VAMP7, a protein that plays a crucial role in membrane fusion and intracellular vesicle trafficking. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunofluorescence applications.VAMP7, also known as vesicle-associated membrane protein 7, is a key component of the cellular machinery responsible for transporting and delivering essential molecules within cells. Its functions are critical for various cellular processes, including neurotransmitter release, hormone secretion, and immune responses.
By targeting VAMP7 with this antibody, researchers can gain insights into its role in cellular function and its potential implications in diseases like neurodegenerative disorders, diabetes, and cancer.Understanding the mechanisms of VAMP7 is essential for developing targeted therapies that can regulate vesicular trafficking and improve cellular function in diverse physiological and pathological contexts. The VAMP7 Polyclonal Antibody provides researchers with a reliable tool to investigate the functions and regulation of this important protein, advancing our knowledge of cellular biology and disease mechanisms.
Antibody Name:
VAMP7 Antibody (PACO31036)
Antibody SKU:
PACO31036
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Chicken
Immunogen:
Recombinant Chicken Vesicle-associated membrane protein 7 protein (2-181AA)
Immunohistochemistry of paraffin-embedded mouse liver tissue using PACO31036 at dilution of 1:50.
Background:
Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for focal exocytosis of late endocytic vesicles during phagosome formation
Synonyms:
Vesicle-associated membrane protein 7 (Synaptobrevin-like protein 1), VAMP7, SYBL1
UniProt Protein Function:
Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for focal exocytosis of late endocytic vesicles during phagosome formation ().
