The VAMP4 Polyclonal Antibody (CAB4241) is a valuable tool for researchers studying VAMP4, a protein involved in membrane trafficking and vesicle fusion. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the VAMP4 protein, this antibody enables the detection and analysis of VAMP4 in various cell types, making it an excellent choice for studies in cell biology and neuroscience.VAMP4, also known as vesicle-associated membrane protein 4, plays a critical role in intracellular vesicle trafficking and fusion processes. Its involvement in these fundamental cellular processes makes it a key player in diverse biological functions, including neurotransmitter release, hormone secretion, and organelle dynamics.
Understanding the function of VAMP4 is essential for unraveling the mechanisms underlying these processes and their implications in health and disease.Researchers studying vesicle trafficking, membrane fusion, and organelle dynamics will benefit from the specificity and reliability of the VAMP4 Polyclonal Antibody (CAB4241) in their experiments. Its versatility and sensitivity make it a valuable tool for investigating the intricate mechanisms governing cellular functions and may lead to new insights into various physiological and pathological processes.
Product Name:
VAMP4 Rabbit Polyclonal Antibody
SKU:
CAB4241
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-115 of human VAMP4 (NP_003753.2).
B cells,HeLa,Jurkat,BT-474,NIH/3T3,Mouse brain,Mouse lung,Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Golgi apparatus, Single-pass type IV membrane protein, trans-Golgi network membrane.
Calculated MW:
16kDa
Observed MW:
16kDa
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport.
Purification Method:
Affinity purification
Gene ID:
8674
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using VAMP4 antibody (CAB4241) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
