UniProt Protein Function: | VAMP1: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Belongs to the synaptobrevin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 12p Cellular Component: cell junction; cell surface; cytosol; integral to plasma membrane; mitochondrial outer membrane; synaptic vesicle membrane; terminal button Molecular Function:protein binding; SNAP receptor activity; SNARE binding Biological Process: vesicle fusion Disease: Spastic Ataxia 1, Autosomal Dominant |
NCBI Summary: | Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in this gene are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2014] |
UniProt Code: | P23763 |
NCBI GenInfo Identifier: | 135093 |
NCBI Gene ID: | 6843 |
NCBI Accession: | P23763.1 |
UniProt Secondary Accession: | P23763,O75468, Q15857, Q6FG94, Q8IVC9, A8MVP3, D3DUR3 |
UniProt Related Accession: | P23763 |
Molecular Weight: | 12,658 Da |
NCBI Full Name: | Vesicle-associated membrane protein 1 |
NCBI Synonym Full Names: | vesicle associated membrane protein 1 |
NCBI Official Symbol: | VAMP1Â Â |
NCBI Official Synonym Symbols: | SYB1; SPAX1; VAMP-1Â Â |
NCBI Protein Information: | vesicle-associated membrane protein 1 |
UniProt Protein Name: | Vesicle-associated membrane protein 1 |
UniProt Synonym Protein Names: | Synaptobrevin-1 |
Protein Family: | Vesicle-associated membrane protein |
UniProt Gene Name: | VAMP1Â Â |
UniProt Entry Name: | VAMP1_HUMAN |